Artitis

1. Clinical Trial for Severely Ill COVID-19 Patients Now Underway at Montefiore-Einstein

   (BRONX, NY)—April 3, 2020—Montefiore Health System andAlbert Einstein College of Medicine has started treating very sick COVID-19 patients as part of a multicenter trial evaluating a potential therapy for the new disease. The double-blind, placebo-controlled trial is testing whether sarilumab, a drug already approved for treating rheumatoid arthritis, can halt the inflammation that can overwhelm the lungs of COVID-19 patients. A very similar drug yielded promising results in a recent study involving patients in China. (Source: Einstein News)

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2. Vitamin D Might Aid Seniors' Recovery From Hip Fracture: Study

   Title: Vitamin D Might Aid Seniors' Recovery From Hip Fracture: StudyCategory: Health NewsCreated: 4/2/2020 12:00:00 AMLast Editorial Review: 4/3/2020 12:00:00 AM (Source: MedicineNet Arthritis General)

3. Modifiable Risk Factors for Development of Psoriatic Arthritis Modifiable Risk Factors for Development of Psoriatic Arthritis

   This study examined weight reduction as well as smoking as potential modifiable risk factors for PsA.The British Journal of Dermatology (Source: Medscape Today Headlines)

4. Demand surge for 'game changer' COVID-19 drug hydroxychloroquine despite lack of clinical evidence

   Though there have been no large-scale clinical trials of the drug's efficacy in treating coronavirus, chemists all over say they are facing a shortage of the medicine, not so long ago known mainly to those who had malaria or were prescribed it for arthritis pain. While the demand for hydrochloroqine has seen a rapid uptick, the safety and effectiveness of the drug in treating COVID-19 still remains a concern. (Source: The Economic Times Healthcare and Biotech News)

5. Navidea signs WorldCare, gets 'going concern' warning

   Radiopharmaceutical developer Navidea Biopharmaceuticals has inked a letter...Read more on AuntMinnie.comRelated Reading: Navidea gets 5-year patent extension for Lymphoseek Navidea raises $7.6M, regains listing compliance Navidea claims victories in legal case with former CEO Navidea signs immunotherapy deal with IMV Navidea highlights rheumatoid arthritis results (Source: AuntMinnie.com Headlines)

6. Sanofi, Regeneron Expand Testing of Potential Coronavirus Treatment Sanofi, Regeneron Expand Testing of Potential Coronavirus Treatment

   Sanofi and Regeneron Pharmaceuticals Inc have expanded a clinical trial of their rheumatoid arthritis drug Kevzara as a coronavirus treatment to patients outside the United States.Reuters Health Information (Source: Medscape Critical Care Headlines)

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7. Individuals taking class of steroid medications at high risk for COVID-19

   (The Endocrine Society) Individuals taking a class of steroid hormones called glucocorticoids for conditions such as asthma, allergies and arthritis on a routine basis may be unable to mount a normal stress response and are at high risk if they are infected with the virus causing COVID-19, according to a new editorial published in the Endocrine Society's Journal of Clinical Endocrinology& Metabolism. (Source: EurekAlert! - Medicine and Health)

8. Sanofi, Regeneron expand testing of potential coronavirus treatment

   Sanofi and Regeneron Pharmaceuticals Inc have expanded a clinical trial of their rheumatoid arthritis drug Kevzara as a coronavirus treatment to patients outside the United States. (Source: Reuters: Health)

9. I ’ve Seen Wars and Epidemics Unfold. But Now That I Have an Immunocompromised Partner, the Coronavirus Makes Me Truly Scared

   At midnight on Thursday March 26, all of South Africa went into lockdown. For the next 21 days, no one is to leave their homes unless they are going to the grocery store, the pharmacy or to seek medical help. No dog walking, no jogging, no food delivery services. Only essential workers are exempt, and that list is small. When President Cyril Ramaphosa made the announcement on March 23, a week after shutting the nation’s schools, there were only 402 confirmed COVID-19 cases. But it was essential, he said, to “flatten the curve” before widespread outbreaks overwhelmed the country’s fragile medical system. By the time the lockdown went into effect, three days later, the number of cases had more than doubled. For most South Africans living paycheck to paycheck (if they...

10. A simple screening test to assess risk of falls in Japanese patients with rheumatoid arthritis: results from the IORRA cohort study - Oh K, Furuya T, Inoue E, Tanaka E, Ikari K, Taniguchi A, Yamanaka H, Okazaki K, Harigai M.

    [Abstract unavailable] Language: en... (Source: SafetyLit)

11. President Trump Called Hydroxychloroquine a ‘Game Changer,’ But Experts Warn Against Self-Medicating With the Drug. Here’s What You Need to Know

    After President Trump, late last week, expressed great confidence in the promise of a new COVID-19 therapy that combines two existing prescription medications, supplies of these two drugs rapidly began disappearing from pharmacy shelves. The U.S. Food and Drug Administration allowed an Indian company previously restricted from importing drug products into the US to now start manufacturing one of the drugs. And U.S. plants began gearing up to produce enough to meet the surge in demand. But in those few days, a few people who began self medicating with the drugs in an effort to prevent COVID-19 have died, and others have been hospitalized. These tragedies have raised questions about the safety of the drug combo, and how valid they are as a possible solution to treating COVID-19. The combina...

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12. Man Dies After Taking Chloroquine for Coronavirus

    Chloroquine is approved in the United States to treat malaria, lupus and rheumatoid arthritis, but President Donald Trump has promoted it as a possible treatment for COVID-19, CNN reported. (Source: WebMD Health)

13. Seasonality and Fatigue, Pain, Dryness in Sjogren's Syndrome Seasonality and Fatigue, Pain, Dryness in Sjogren's Syndrome

    In what ways might seasonal variations impact these symptoms in patients with primary Sjogren's syndrome?Arthritis Research & Therapy (Source: Medscape Today Headlines)

14. Taking Steroids for Rheumatoid Arthritis, IBD? Your Odds for Hypertension May Rise

    Title: Taking Steroids for Rheumatoid Arthritis, IBD? Your Odds for Hypertension May RiseCategory: Health NewsCreated: 3/23/2020 12:00:00 AMLast Editorial Review: 3/24/2020 12:00:00 AM (Source: MedicineNet Arthritis General)

15. Why Hoarding Of Hydroxychloroquine Needs To Stop

    Despite Trump's public remarks, infectious disease experts say it's premature to think hydroxychloroquine will help against COVID-19. And patients with lupus or rheumatoid arthritis rely on the drug.(Image credit: NIAID/Flickr) (Source: NPR Health and Science)

16. My Life With RA

    One woman tells how she has learned to live fully with Rheumatoid Arthritis. (Source: WebMD Health)

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17. Taking Steroids for Rheumatoid Arthritis, IBD? Your Odds for Hypertension May Rise

    MONDAY, March 23, 2020 -- People taking steroids to treat chronic inflammatory diseases are at high risk for developing high blood pressure, British investigators report. Inflammatory bowel disease and rheumatoid arthritis are often treated with... (Source: Drugs.com - Daily MedNews)

18. Upadacitinib Promising in Resistant Rheumatoid Arthritis

    No abstract available (Source: Lippincott's Bone and Joint Newsletter)

19. Trump ’s Embrace of Unproven Drugs to Treat Coronavirus Defies Science

    Doctors and patients also worry that the president ’s rosy outlook for the treatments will exacerbate shortages of old malaria drugs relied on by patients with lupus and other debilitating conditions. (Source: NYT Health)

20. Roche test Actemra in coronavirus patients as firms re-purpose drugs

    Roche will test its arthritis drug Actemra in patients with coronavirus-linked pneumonia, the Swiss drugmaker said on Thursday, joining other pharmaceutical companies seeking to re-purpose existing medicines to fight the epidemic. (Source: Reuters: Health)